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Thomas H Claus Selected Research

Quinazolinones

10/2007Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity.

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Thomas H Claus Research Topics

Disease

5Type 2 Diabetes Mellitus (MODY)
02/2007 - 05/2002
2Body Weight (Weight, Body)
11/2007 - 10/2007
1Weight Gain
11/2007
1Weight Loss (Weight Reduction)
11/2007
1Obesity
10/2007
1Hyperglycemia
12/2005
1Insulin Resistance
12/2005

Drug/Important Bio-Agent (IBA)

5Glucose (Dextrose)FDA LinkGeneric
11/2007 - 05/2002
4Peptides (Polypeptides)IBA
11/2007 - 05/2006
2Ghrelin ReceptorsIBA
11/2007 - 10/2007
2SecretagoguesIBA
11/2007 - 02/2007
2Insulin (Novolin)FDA Link
02/2007 - 05/2002
2Lys(15)-Arg(16)-Leu(27)- vasoactive intestinal peptide (1-7)-GRF (8-27)IBA
02/2007 - 05/2002
1neuropeptide Y2 receptorIBA
11/2007
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
11/2007
1AdiponectinIBA
11/2007
1GhrelinIBA
11/2007
1QuinazolinonesIBA
10/2007
1Glucagon-Like Peptide-1 ReceptorIBA
02/2007
1Glucagon Receptors (Glucagon Receptor)IBA
02/2007
1p66 - pituitary adenylate cyclase-activating peptide analogIBA
02/2007
1Glucagon-Like Peptide 1 (GLP 1)IBA
05/2006
1Glucagon (Glukagon)FDA Link
05/2006
1Fatty Acids (Saturated Fatty Acids)IBA
12/2005
1Nonesterified Fatty Acids (NEFA)IBA
12/2005
1Glycerol (Glycerine)FDA LinkGeneric
12/2005
1Blood Glucose (Blood Sugar)IBA
12/2005
1LipidsIBA
12/2005
1Streptozocin (Streptozotocin)FDA Link
12/2005
1EnzymesIBA
12/2005
1Sterol Esterase (Hormone-Sensitive Lipase)IBA
12/2005

Therapy/Procedure

1Oral Administration
11/2007
1Therapeutics
05/2002